肿瘤精准医学与个性化用药研究团队

CFTR interacts with Hsp90 and regulates the phosphorylation of AKT and ERK1/2 in colorectal cancer cells

2019

期刊 FEBS Open Bio

作者 Kaisheng Liu · Hongtao Jin · Yaomin Guo · Ying Liu · Yong Wan · Pan Zhao · Zhifan Zhou · Jianhong Wang · Maolin Wang · Chang Zou · Weiqing Wu · Zhiqiang Cheng · Yong Dai

Comprehensive Assessment of PD-L1 and PD-L2 Dysregulation Roles in Gastrointestinal Cancer

2019

期刊 SSRN Electronic Journal

作者 Qijie Zhao · Jinan Guo · Yueshui Zhao · Jing Shen · Parham Jabbarzadeh Kaboli · Shixin Xiang · Fukuan Du · Xu Wu · Mingxing Li · Lin Wan · Qinglian Wen · Xiang Li · Chang Zou · Zhangang Xiao · Jing Li · Bo Qin

Defective CFTR promotes intestinal proliferation via inhibition of the hedgehog pathway during cystic fibrosis

2019

期刊 Cancer Letters

作者 Kaisheng Liu · Xiao Wang · Chang Zou · Jieting Zhang · Hao Chen · Lailing Tsang · Mei Kuen Yu · Yiu Wa Chung · Jianhong Wang · Yong Dai · Yang Liu · Xiaohu Zhang

Determination of the complexity and diversity of the TCR β‑chain CDR3 repertoire in bladder cancer using high‑throughput sequencing

2019

期刊 Oncology Letters

作者 Jingsheng Ma · Guoping Sun · Peng Zhu · Song Liu · Minglin Ou · Zhiqiang Chen · Chang Zou · Frank Chan · Yong Dai · Weiguo Sui

Establishment and Characterization of a CTC Cell Line from Peripheral Blood of Breast Cancer Patient

2019

期刊 Journal of Cancer

作者 Pan Zhao · Wenbin Zhou · Chang Liu · Huirong Zhang · Zhiqiang Cheng · Weiqing Wu · Kaisheng Liu · Hong Hu · Caineng Zhong · Yayuan Zhang · Dongxian Zhou · Feiyuan Liu · Yong Dai · Jianhong Wang · Chang Zou

Isovitexin reduces carcinogenicity and stemness in hepatic carcinoma stem-like cells by modulating MnSOD and FoxM1

2019

期刊 Journal of Experimental & Clinical Cancer Research

作者 Xiaocheng Cao · Lihua Liu · Qing Yuan · Xiang Li · Yinghong Cui · Kaiqun Ren · Chang Zou · A. Chen · Chang Xu · Yebei Qiu · Meifang Quan · Jiansong Zhang · Jianguo Cao · Xiangding Chen

Multifunctional Nanoengineered Hydrogels Consisting of Black Phosphorus Nanosheets Upregulate Bone Formation

2019

期刊 Small

作者 Zhenming Wang · Jin Zhao · Wanze Tang · Liqiu Hu · Xin Chen · Yiping Su · Chang Zou · Jianhong Wang · William W. Lu · Wanxin Zhen · Ronghua Zhang · Dazhi Yang · Songlin Peng

Pathogenic variants of PROC gene caused type I activity deficiency in a familial Chinese venous thrombosis

2019

期刊 Journal of Cellular and Molecular Medicine

作者 Yongjian Yue · Shengguo Liu · Xuemei Han · Lu Xiao · Qijun Huang · Shulin Li · Kaixue Zhuang · Mo Yang · Chang Zou · Yingyun Fu

Promoter hypermethylation of the CFTR gene as a novel diagnostic and prognostic marker of breast cancer

2019

期刊 Cell Biology International

作者 Kaisheng Liu · Fajin Dong · Hengyuan Gao · Yaomin Guo · Haili Li · Fang Yang · Pan Zhao · Yong Dai · Jianhong Wang · Wenbin Zhou · Chang Zou

Single-cell transcriptional profiling reveals the heterogenicity in colorectal cancer

2019

期刊 Medicine

作者 Weier Dai · Fangbin Zhou · Donge Tang · Liewen Lin · Chang Zou · Wenyong Tan · Yong Dai

Targeting autophagy enhances the anticancer effect of artemisinin and its derivatives

2019

期刊 Medicinal Research Reviews

作者 Xin Sun · Peiyi Yan · Chang Zou · Yin‐Kwan Wong · Yuhan Shu · Yew Mun Lee · Chongjing Zhang · Nai‐Di Yang · Jigang Wang · Jianbin Zhang

The High-Risk HPV Oncogene E7 Upregulates miR-182 Expression Through the TGF-β/Smad Pathway in Cervical Cancer

2019

期刊 SSRN Electronic Journal

作者 Jiao Chen · Yan Deng · Liangfei Ao · Yi Song · Yan Xu · Chi Chiu Wang · Kwong Wai Choy · Kwok Hung Tony Chung · Quan Du · Yi Sui · Tao Yang · Jing Yang · Tao Tang

Association of the characteristics of B‑ and T‑cell repertoires with papillary thyroid carcinoma

2018

期刊 Oncology Letters

作者 Guoping Sun · Lumei Qiu · Zhiqiang Cheng · Weibing Pan · Jingjun Qiu · Chang Zou · Ni Xie · Song Liu · Peng Zhu · Jun Zeng · Yong Dai

Development of a novel and economical agar-based non-adherent three-dimensional culture method for enrichment of cancer stem-like cells

2018

期刊 Stem Cell Research & Therapy

作者 Weijie Gao · Dinglan Wu · Yuliang Wang · Zhu Wang · Chang Zou · Yong Dai · Chi-Fai Ng · Jeremy Yuen-Chun Teoh · Franky Leung Chan

LRH-1 drives hepatocellular carcinoma partially through induction of c-myc and cyclin E1, and suppression of p21

2018

期刊 Cancer Management and Research

作者 Lijia Xiao · Yuliang Wang · Weicheng Liang · Liping Liu · Nannan Pan · Huimin Deng · Luqian Li · Chang Zou · Franky Leung Chan · Yiwen Zhou

MIR31HG promotes cell proliferation and invasion by activating the Wnt/β‑catenin signaling pathway in non‑small cell lung cancer

2018

期刊 Oncology Letters

作者 Shuaiyu Zheng · Xiaojin Zhang · Xian Wang · Jiyuan Li

Nuclear receptor ERRα and transcription factor ERG form a reciprocal loop in the regulation of TMPRSS2:ERG fusion gene in prostate cancer

2018

期刊 Oncogene

作者 Zhenyu Xu · Yuliang Wang · Zhan Gang Xiao · Chang Zou · Xian Zhang · Zhu Wang · Dinglan Wu · Shan Yu · Franky Leung Chan

Orphan nuclear receptor TLX contributes to androgen insensitivity in castration-resistant prostate cancer via its repression of androgen receptor transcription

2018

期刊 Oncogene

作者 Lin Jia · Dinglan Wu · Yuliang Wang · Wenxing You · Zhu Wang · Lijia Xiao · Ganhui Cai · Zhenyu Xu · Chang Zou · Fei Wang · Jeremy Yuen-Chun Teoh · Chi-Fai Ng · Shan Yu · Franky L Chan

Prognostic role of neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in prostate cancer: A meta-analysis of results from multivariate analysis

2018

期刊 International Journal of Surgery

作者 Jinan Guo · Jiequn Fang · Xiangjiang Huang · Yanfeng Liu · Yeqing Yuan · Xueqi Zhang · Chang Zou · Kefeng Xiao · Jianhong Wang

Correlation of choroidal thickness and ametropiain young adolescence

2017

期刊 PLOS ONE

作者 Xiaolei Shao · Chang Zou · Bo Qin

Nasopharyngeal carcinoma treated with bevacizumab combined with paclitaxel liposome plus cisplatin: a case report and literature review

2016

期刊 OncoTargets and Therapy

作者 Wan He · Chang Zou · Zhongkai Tian · Wenyong Tan · Weixi Shen · Jinghua Chen · Liping Liu · Ruilian Xu

Endostar attenuates melanoma tumor growth via its interruption of b-FGF mediated angiogenesis

2015

期刊 Cancer Letters

作者 Lijia Xiao · Shucai Yang · Jianhua Hao · Xue Yuan · Wei Luo · Liping Jiang · Yang Hu · Zhongping Fu · Yun Zhang · Chang Zou

Orphan nuclear receptor TLX functions as a potent suppressor of oncogene-induced senescence in prostate cancer via its transcriptional co-regulation of the CDKN1A (p21WAF1 / CIP1 ) and SIRT1 genes

2015

期刊 The Journal of Pathology

作者 Dinglan Wu · Shan Yu · Lin Jia · Chang Zou · Zhenyu Xu · Lijia Xiao · Kam-Bo Wong · Chi-Fai Ng · Franky L Chan

ERRαaugments HIF-1 signalling by directly interacting with HIF-1αin normoxic and hypoxic prostate cancer cells

2014

期刊 The Journal of Pathology

作者 Chang Zou · Shan Yu · Zhenyu Xu · Dinglan Wu · Chi-Fai Ng · Xiaoqiang Yao · David T Yew · Jean-Marc Vanacker · Franky L Chan

Ion channel TRPM8 promotes hypoxic growth of prostate cancer cells via an O2-independent and RACK1-mediated mechanism of HIF-1α stabilization

2014

期刊 The Journal of Pathology

作者 Shan Yu · Zhenyu Xu · Chang Zou · Dinglan Wu · Yuliang Wang · Xiaoqiang Yao · Chi-Fai Ng · Franky L Chan

Transient receptor potential channel TRPC5 is essential for P-glycoprotein induction in drug-resistant cancer cells

2012

期刊 Proceedings of the National Academy of Sciences

作者 X. Ma · Y. Cai · D. He · C. Zou · P. Zhang · C. Y. Lo · Z. Xu · F. L. Chan · S. Yu · Y. Chen · R. Zhu · J. Lei · J. Jin · X. Yao

17-Beta-estradiol induces neoplastic transformation in prostatic epithelial cells

2011

期刊 Cancer Letters

作者 Shan Yu · Yan Zhang · Mong-Ting Yuen · Chang Zou · David Danielpour · Franky L Chan

N-terminal modification increases the stability of the recombinant human endostatinin vitro

2009

期刊 Biotechnology and Applied Biochemistry

作者 Li‑Ping Jiang · Chang Zou · Xue Yuan · Wei Luo · Yong Wen · Yali Chen

Development of Internet-Accessible Prediction Models for Prostate Cancer Diagnosis, Treatment, and Follow-Up

2003

技术报告

作者 Leon Sun · Judd W. Moul · Hongyu Wu · Fatiha Bensouda · Holly Wu

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CFTR interacts with Hsp90 and regulates the phosphorylation of AKT and ERK1/2 in colorectal cancer cells

Comprehensive Assessment of PD-L1 and PD-L2 Dysregulation Roles in Gastrointestinal Cancer

Defective CFTR promotes intestinal proliferation via inhibition of the hedgehog pathway during cystic fibrosis

Determination of the complexity and diversity of the TCR β‑chain CDR3 repertoire in bladder cancer using high‑throughput sequencing

Establishment and Characterization of a CTC Cell Line from Peripheral Blood of Breast Cancer Patient

Isovitexin reduces carcinogenicity and stemness in hepatic carcinoma stem-like cells by modulating MnSOD and FoxM1

Multifunctional Nanoengineered Hydrogels Consisting of Black Phosphorus Nanosheets Upregulate Bone Formation

Pathogenic variants of PROC gene caused type I activity deficiency in a familial Chinese venous thrombosis

Promoter hypermethylation of the CFTR gene as a novel diagnostic and prognostic marker of breast cancer

Single-cell transcriptional profiling reveals the heterogenicity in colorectal cancer

Targeting autophagy enhances the anticancer effect of artemisinin and its derivatives

The High-Risk HPV Oncogene E7 Upregulates miR-182 Expression Through the TGF-β/Smad Pathway in Cervical Cancer

Association of the characteristics of B‑ and T‑cell repertoires with papillary thyroid carcinoma

Development of a novel and economical agar-based non-adherent three-dimensional culture method for enrichment of cancer stem-like cells

LRH-1 drives hepatocellular carcinoma partially through induction of c-myc and cyclin E1, and suppression of p21

MIR31HG promotes cell proliferation and invasion by activating the Wnt/β‑catenin signaling pathway in non‑small cell lung cancer

Nuclear receptor ERRα and transcription factor ERG form a reciprocal loop in the regulation of TMPRSS2:ERG fusion gene in prostate cancer

Orphan nuclear receptor TLX contributes to androgen insensitivity in castration-resistant prostate cancer via its repression of androgen receptor transcription

Prognostic role of neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in prostate cancer: A meta-analysis of results from multivariate analysis

Correlation of choroidal thickness and ametropiain young adolescence

Nasopharyngeal carcinoma treated with bevacizumab combined with paclitaxel liposome plus cisplatin: a case report and literature review

Endostar attenuates melanoma tumor growth via its interruption of b-FGF mediated angiogenesis

Orphan nuclear receptor TLX functions as a potent suppressor of oncogene-induced senescence in prostate cancer via its transcriptional co-regulation of the CDKN1A (p21WAF1 / CIP1 ) and SIRT1 genes

ERRαaugments HIF-1 signalling by directly interacting with HIF-1αin normoxic and hypoxic prostate cancer cells

Ion channel TRPM8 promotes hypoxic growth of prostate cancer cells via an O2-independent and RACK1-mediated mechanism of HIF-1α stabilization

Transient receptor potential channel TRPC5 is essential for P-glycoprotein induction in drug-resistant cancer cells

17-Beta-estradiol induces neoplastic transformation in prostatic epithelial cells

N-terminal modification increases the stability of the recombinant human endostatinin vitro

Development of Internet-Accessible Prediction Models for Prostate Cancer Diagnosis, Treatment, and Follow-Up