array(2) { ["lab"]=> string(3) "586" ["publication"]=> string(4) "3507" } Palladium-Catalyzed Regioselective Olefination of O-Acetyl Cyanohydrins - 姜兵 | LabXing

Palladium-Catalyzed Regioselective Olefination of O-Acetyl Cyanohydrins

2018
期刊 The Journal of Organic Chemistry
A practical palladium-catalyzed ortho-olefination of O-acetyl cyanohydrins assisted by synergetic directing groups has been developed. Thus, a range of olefinated O-acetyl cyanohydrins were synthesized in moderate to good yields. The reaction occurs efficiently with high regioselectivity and with a satisfactory tolerance of functional groups.