array(2) { ["lab"]=> string(3) "832" ["publication"]=> string(5) "12302" } Pd/Cu-Catalyzed Cascade C(sp3)–H Arylation and Intramolecular C–N Coupling: A One-Pot Synthesis of 3,4-2H-Quinolinone Skeletons - 新型多组学研究综合实验室（王晓东课题组） | LabXing

新型多组学研究综合实验室（王晓东课题组）

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大学 中央民族大学 / 生命与环境科学学院
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Pd/Cu-Catalyzed Cascade C(sp3)–H Arylation and Intramolecular C–N Coupling: A One-Pot Synthesis of 3,4-2H-Quinolinone Skeletons

2019
期刊 Organic Letters
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In this letter, we successfully explored a cascade Pd/Cu-catalyzed intermolecular C(sp(3))-H arylation of amides and intramolecular C-N coupling reaction. This method provides a one-pot strategy to synthesize 3,4-2 H-quinolinone with good regioselectivity of C-H arylation and C-N coupling from C-I and C-X bonds from readily available starting materials.

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