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#Ruiwen Zhang
Novel natural product therapeutics targeting both inflammation and cancer
胃癌基础与临床转化研究实验室 , 中国科学院
Inhibiting NFAT1 for breast cancer therapy: New insights into the mechanism of action of MDM2 inhibitor JapA
胃癌基础与临床转化研究实验室 , 中国科学院
Identification of a new class of natural product MDM2 inhibitor: In vitro and in vivo anti-breast cancer activities and target validation
胃癌基础与临床转化研究实验室 , 中国科学院
Abstract 2433: A novel MDM2 inhibitor suppresses breast cancer growth and metastasis
胃癌基础与临床转化研究实验室 , 中国科学院
Abstract 2434: The anticancer activity of Japonicone A is mediated by inhibiting NFAT1-MDM2 pathway
胃癌基础与临床转化研究实验室 , 中国科学院
Abstract C93: RYBP predicts survival of patients with non-small cell lung cancer and sensitizes chemotherapy
胃癌基础与临床转化研究实验室 , 中国科学院
Abstract 4863: Targeting the NFAT1-MDM2-MDMX network for prostate cancer therapy
胃癌基础与临床转化研究实验室 , 中国科学院
Experimental Therapy of Advanced Breast Cancer: Targeting NFAT1–MDM2–p53 Pathway
胃癌基础与临床转化研究实验室 , 中国科学院
Inulanolide A as a new dual inhibitor of NFAT1-MDM2 pathway for breast cancer therapy
胃癌基础与临床转化研究实验室 , 中国科学院
Preclinical pharmacology of novel indolecarboxamide ML-970, an investigative anticancer agent
胃癌基础与临床转化研究实验室 , 中国科学院
Natural Product Ginsenoside 25-OCH3-PPD Inhibits Breast Cancer Growth and Metastasis through Down-Regulating MDM2
胃癌基础与临床转化研究实验室 , 中国科学院
Abstract 5266: RYBP expression predicts survival of patients with hepatocellular carcinoma, and regulates response to chemotherapy
胃癌基础与临床转化研究实验室 , 中国科学院
Abstract 4867: Treating hepatocellular carcinoma metastasis and overcoming chemoresistance through inhibiting the MDM2 oncogene
胃癌基础与临床转化研究实验室 , 中国科学院
Abstract 3858: Inflammation and oncogene in hepatocellular carcinoma: Clinical relevance and experimental targeted therapy
胃癌基础与临床转化研究实验室 , 中国科学院
Identification of the ZAK-MKK4-JNK-TGFβ Signaling Pathway as a Molecular Target for Novel Synthetic Iminoquinone Anticancer Compound BA-TPQ
胃癌基础与临床转化研究实验室 , 中国科学院
miRNAs in Cancer Prevention and Treatment and as Molecular Targets for Natural Product Anticancer Agents
胃癌基础与临床转化研究实验室 , 中国科学院
The pyrido[b]indole MDM2 inhibitor SP-141 exerts potent therapeutic effects in breast cancer models
胃癌基础与临床转化研究实验室 , 中国科学院
JKA97, a Novel Benzylidene Analog of Harmine, Exerts Anti-Cancer Effects by Inducing G1 Arrest, Apoptosis, and p53-Independent Up-Regulation of p21
胃癌基础与临床转化研究实验室 , 中国科学院
Identification of a New Class of MDM2 Inhibitor That Inhibits Growth of Orthotopic Pancreatic Tumors in Mice
胃癌基础与临床转化研究实验室 , 中国科学院
Prevention of prostate cancer by natural product MDM2 inhibitor GS25: in vitro and in vivo activities and molecular mechanisms
胃癌基础与临床转化研究实验室 , 中国科学院
Oral nano-delivery of anticancer ginsenoside 25-OCH3-PPD, a natural inhibitor of the MDM2 oncogene: Nanoparticle preparation, characterization, in vitro and in vivo anti-prostate cancer activity, and mechanisms of action
胃癌基础与临床转化研究实验室 , 中国科学院
Targeting MDM2 for novel molecular therapy: Beyond oncology
胃癌基础与临床转化研究实验室 , 中国科学院
MDM2-NFAT1 dual inhibitor, MA242: Effective against hepatocellular carcinoma, independent of p53
胃癌基础与临床转化研究实验室 , 中国科学院
Targeting the NFAT1-MDM2-MDMX Network Inhibits the Proliferation and Invasion of Prostate Cancer Cells, Independent of p53 and Androgen
胃癌基础与临床转化研究实验室 , 中国科学院
A novel inhibitor of MDM2 oncogene blocks metastasis of hepatocellular carcinoma and overcomes chemoresistance
胃癌基础与临床转化研究实验室 , 中国科学院
A quantitative LC-MS/MS method for determination of SP-141, a novel pyrido[b]indole anticancer agent, and its application to a mouse PK study
胃癌基础与临床转化研究实验室 , 中国科学院
Oral delivery of anti-MDM2 inhibitor SP141-loaded FcRn-targeted nanoparticles to treat breast cancer and metastasis
胃癌基础与临床转化研究实验室 , 中国科学院
Inhibiting β-Catenin by β-Carboline-Type MDM2 Inhibitor for Pancreatic Cancer Therapy
胃癌基础与临床转化研究实验室 , 中国科学院
Discovery and Characterization of Dual Inhibitors of MDM2 and NFAT1 for Pancreatic Cancer Therapy
胃癌基础与临床转化研究实验室 , 中国科学院
Natural products targeting the p53-MDM2 pathway and mutant p53: Recent advances and implications in cancer medicine
胃癌基础与临床转化研究实验室 , 中国科学院
Highly efficient delivery of potent anticancer iminoquinone derivative by multilayer hydrogel cubes
胃癌基础与临床转化研究实验室 , 中国科学院
Polycomb Group (PcG) Proteins and Human Cancers: Multifaceted Functions and Therapeutic Implications
胃癌基础与临床转化研究实验室 , 中国科学院
RYBP predicts survival of patients with non-small cell lung cancer and regulates tumor cell growth and the response to chemotherapy
胃癌基础与临床转化研究实验室 , 中国科学院
Development and validation of an HPLC-MS/MS analytical method for quantitative analysis of TCBA-TPQ, a novel anticancer makaluvamine analog, and application in a pharmacokinetic study in rats
胃癌基础与临床转化研究实验室 , 中国科学院
NFAT as cancer target: Mission possible?
胃癌基础与临床转化研究实验室 , 中国科学院
Development and validation of a rapid HPLC method for quantitation of SP-141, a novel pyrido[b]indole anticancer agent, and an initial pharmacokinetic study in mice
胃癌基础与临床转化研究实验室 , 中国科学院
RYBP expression is associated with better survival of patients with hepatocellular carcinoma (HCC) and responsiveness to chemotherapy of HCC cells in vitro and in vivo
胃癌基础与临床转化研究实验室 , 中国科学院
Selective cytotoxicity, inhibition of cell cycle progression, and induction of apoptosis in human breast cancer cells by sesquiterpenoids from Inula lineariifolia Turcz.
胃癌基础与临床转化研究实验室 , 中国科学院