猪功能基因组学研究实验室

Integrative analysis of transcriptomic and metabolomic profiles reveal the complex molecular regulatory network of meat quality in Enshi black pigs

2022

期刊 Meat Science

作者 Huiwen Zhan · Youcai Xiong · Zichang Wang · Wenjun Dong · Qichao Zhou · Shengsong Xie · Xinyun Li · Shuhong Zhao · Yunlong Ma

CMAS and ST3GAL4 Play an Important Role in the Adsorption of Influenza Virus by Affecting the Synthesis of Sialic Acid Receptors

2021

期刊 International Journal of Molecular Sciences

作者 Yaxin Zhao · Jiahui Zou · Qingxia Gao · Shengsong Xie · Jiyue Cao · Hongbo Zhou

The Advancements, Challenges and Future Implications of the CRISPR/Cas9 System in Swine Research

2021

期刊 Journal of Genetics and Genomics

作者 Jinfu Zhang · Emmanuel M. Khazalwa · Hussein M. Abkallo · Yuan Zhou · Xiongwei Nie · Jinxue Ruan · Changzhi Zhao · Jieru Wang · Jing Xu · Xinyun Li · Shuhong Zhao · Erwei Zuo · Lucilla Steinaa · Shengsong Xie

Application of CRISPR-Cas12a Enhanced Fluorescence Assay Coupled with Nucleic Acid Amplification for the Sensitive Detection of African Swine Fever Virus

2020

期刊 ACS Synthetic Biology

作者 Dagang Tao · Jiajia Liu · Xiongwei Nie · Bingrong Xu · Thuy-Nhien Tran-Thi · Lili Niu · Xiangdong Liu · Jinxue Ruan · Xiaochen Lan · Guiqing Peng · Limeng Sun · Yunlong Ma · Xinyun Li · Congcong Li · Shuhong Zhao · Shengsong Xie

CRISPR screening of porcine sgRNA library identifies host factors associated with Japanese encephalitis virus replication

2020

期刊 Nature Communications

作者 Changzhi Zhao · Hailong Liu · Tianhe Xiao · Zichang Wang · Xiongwei Nie · Xinyun Li · Ping Qian · Liuxing Qin · Xiaosong Han · Jinfu Zhang · Jinxue Ruan · Mengjin Zhu · Yi-Liang Miao · Bo Zuo · Kui Yang · Shengsong Xie · Shuhong Zhao

Enhancing the antibacterial activities of sow milk via site-specific knock-in of a lactoferrin gene in pigs using CRISPR/Cas9 technology

2020

期刊 Cell & Bioscience

作者 Xiaosong Han · Yang Gao · Guanglei Li · Youcai Xiong · Changzhi Zhao · Jinxue Ruan · Yunlong Ma · Xinyun Li · Changchun Li · Shuhong Zhao · Shengsong Xie

Genome editing with the CRISPR‐Cas system: an art, ethics and global regulatory perspective

2020

期刊 Plant Biotechnology Journal

作者 Debin Zhang · Amjad Hussain · Hakim Manghwar · Kabin Xie · Shengsong Xie · Shuhong Zhao · Robert M. Larkin · Ping Qing · Shuangxia Jin · Fang Ding

Genome-Wide Patterns of Homozygosity and Relevant Characterizations on the Population Structure in Piétrain Pigs

2020

期刊 Genes

作者 Huiwen Zhan · Saixian Zhang · Kaili Zhang · Xia Peng · Shengsong Xie · Xinyun Li · Shuhong Zhao · Yunlong Ma

Identification of ACTB Gene as a Potential Safe Harbor Locus in Pig Genome

2020

期刊 Molecular Biotechnology

作者 Youcai Xiong · Xiaosong Han · Jinfu Zhang · Guangxing Zhao · Zichang Wang · Rongzhi Zhuang · Xiongwei Nie · Shengsong Xie · Changchun Li · Xinyun Li · Xiangdong Liu · Kui Li · Shuhong Zhao · Jinxue Ruan

Knockout of glutathione peroxidase 5 down-regulates the piRNAs in the caput epididymidis of aged mice

2020

期刊 Asian Journal of Andrology

作者 Yu-Chuan Zhou · Joëlr Drevet · Chen Chu · Lu Yu · Joelle Henry-Berger · Yan-Fei Ru · Ayhan Kocer · Alexandre Champroux · Zhi-Tong Li · Miao He · Sheng-Song Xie · Wu-Bin Ma · Min-Jie Ni · Zi-Mei Ni · Yun-Li Guo · Zhao-Liang Fei · Lan-Tao Gou · Qiang Liu · Samanta Sharma · Yu Zhou · Mo-Fang Liu · Charliedegui Chen · Andrewl Eamens · Brett Nixon · Yong-Lian Zhang

miR-208b modulating skeletal muscle development and energy homoeostasis through targeting distinct targets

2020

期刊 RNA Biology

作者 Liangliang Fu · Heng Wang · Yinlong Liao · Peng Zhou · Yueyuan Xu · Yunxia Zhao · Shengsong Xie · Shuhong Zhao · Xinyun Li

Selective sweep analysis reveals extensive parallel selection traits between large white and Duroc pigs

2020

期刊 Evolutionary Applications

作者 Saixian Zhang · Kaili Zhang · Xia Peng · Huiwen Zhan · Jiahui Lu · Shengsong Xie · Shuhong Zhao · Xinyun Li · Yunlong Ma

Evaluation of the effects of sequence length and microsatellite instability on single-guide RNA activity and specificity

2019

期刊 International Journal of Biological Sciences

作者 Changzhi Zhao · Yunlong Wang · Xiongwei Nie · Xiaosong Han · Hailong Liu · Guanglei Li · Gaojuan Yang · Jinxue Ruan · Yunlong Ma · Xinyun Li · Huijun Cheng · Shuhong Zhao · Yaping Fang · Shengsong Xie

Identification of Glyceraldehyde-3-Phosphate Dehydrogenase Gene as an Alternative Safe Harbor Locus in Pig Genome

2019

期刊 Genes

作者 Xiaosong Han · Youcai Xiong · Changzhi Zhao · Shengsong Xie · Changchun Li · Xinyun Li · Xiangdong Liu · Kui Li · Shuhong Zhao · Jinxue Ruan

Identifying Selection Signatures for Backfat Thickness in Yorkshire Pigs Highlights New Regions Affecting Fat Metabolism

2019

期刊 Genes

作者 Haoran Ma · Saixian Zhang · Kaili Zhang · Huiwen Zhan · Xia Peng · Shengsong Xie · Xinyun Li · Shuhong Zhao · Yunlong Ma

Japanese Encephalitis Virus infection induces inflammation of swine testis through RIG-I—NF-ĸB signaling pathway

2019

期刊 Veterinary Microbiology

作者 Bohan Zheng · Xugang Wang · Yixin Liu · Yunchuan Li · Siwen Long · Changqin Gu · Jing Ye · Shengsong Xie · Shengbo Cao

Production of homeobox A10 gene transgenic pigs by somatic cell nuclear transfer

2019

期刊 Journal of Integrative Agriculture

作者 Qian Xiao · Chang-Zhi Zhao · Rui-Yi Lin · Guang-Lei Li · Chang-Chun Li · Hai-Yan Wang · Jing Xu · Sheng-Song Xie · Mei Yu · Shu-Hong Zhao

Quantification of allelic differential expression using a simple Fluorescence primer PCR-RFLP-based method

2019

期刊 Scientific Reports

作者 Changzhi Zhao · Shengsong Xie · Hui Wu · Yu Luan · Suqin Hu · Juan Ni · Ruiyi Lin · Shuhong Zhao · Dingxiao Zhang · Xinyun Li

A Review of CRISPR-Based Genome Editing: Survival, Evolution and Challenges

2018

期刊 Current Issues in Molecular Biology

作者 Hafiz Ishfaq Ahmad · Muhammad Jamil Ahmad · Akhtar Rasool Asif · Muhammad Adnan · Muhammad Kashif Iqbal · Khalid Mehmood · Sayyed Aun Muhammad · Ali Akbar Bhuiyan · Abdelmotaleb Elokil · Xiaoyong Du · Changzhi Zhao · Xiangdong Liu · Shengsong Xie

CRISPR/Cas9‐mediated genome editing reveals the synergistic effects of β‐defensin family members on sperm maturation in rat epididymis

2018

期刊 The FASEB Journal

作者 Chaobao Zhang · Yuchuan Zhou · Shengsong Xie · Qianqian Yin · Chunhua Tang · Zimei Ni · Jian Fei · Yonglian Zhang

DICER1 regulates antibacterial function of epididymis by modulating transcription of β-defensins

2018

期刊 Journal of Molecular Cell Biology

作者 Chunhua Tang · Minjie Ni · Shengsong Xie · Yao Zhang · Chaobao Zhang · Zimei Ni · Chen Chu · Ligang Wu · Yuchuan Zhou · Yonglian Zhang

Genomic Analysis To Identify Signatures of Artificial Selection and Loci Associated with Important Economic Traits in Duroc Pigs

2018

期刊 G3 Genes|Genomes|Genetics

作者 Yunlong Ma · Saixian Zhang · Kaili Zhang · Chengchi Fang · Shengsong Xie · Xiaoyong Du · Xinyun Li · Debin Ni · Shuhong Zhao

Identifying artificial selection signals in the chicken genome

2018

期刊 PLOS ONE

作者 Yunlong Ma · Lantao Gu · Liubin Yang · Chenghao Sun · Shengsong Xie · Chengchi Fang · Yangzhang Gong · Shijun Li

sRNAPrimerDB: comprehensive primer design and search web service for small non-coding RNAs

2018

期刊 Bioinformatics

作者 Shengsong Xie · Qin Zhu · Wubin Qu · Zhong Xu · Xiangdong Liu · Xinyun Li · Shijun Li · Wubin Ma · Yiliang Miao · Lisheng Zhang · Xiaoyong Du · Wuzi Dong · Haiwei Li · Changzhi Zhao · Yunlong Wang · Yaping Fang · Shuhong Zhao

Alleviation of Toxicity Caused by Overactivation of P parα through P parα -Inducible miR-181a2

2017

期刊 Molecular Therapy - Nucleic Acids

作者 Yanjie Cheng · Zhuying Wei · Shengsong Xie · You Peng · Yi Yan · Dan Qin · Shenghui Liu · Yanling Xu · Guangpeng Li · Lisheng Zhang

CRISPR-offinder: a CRISPR guide RNA design and off-target searching tool for user-defined protospacer adjacent motif

2017

期刊 International Journal of Biological Sciences

作者 Changzhi Zhao · Xiaoguo Zheng · Wubin Qu · Guanglei Li · Xinyun Li · Yi-Liang Miao · Xiaosong Han · Xiangdong Liu · Zhenhua Li · Yunlong Ma · Qianzhi Shao · Haiwei Li · Fei Sun · Shengsong Xie · Shuhong Zhao

Expression of tamoxifen-inducible CRE recombinase in Lcn5-CreERT2 transgenic mouse caput epididymis

2017

期刊 Molecular Reproduction and Development

作者 Juan Xu · Guangxin Yao · Yanfei Ru · Shengsong Xie

Epididymal Region-Specific miRNA Expression and DNA Methylation and Their Roles in Controlling Gene Expression in Rats

2015

期刊 PLOS ONE

作者 Chen Chu · Guangyong Zheng · Shuanggang Hu · Jinsong Zhang · Shengsong Xie · Wubin Ma · Minjie Ni · Chunhua Tang · Lu Zhou · Yuchuan Zhou · Mofang Liu · Yixue Li · Yonglian Zhang

sgRNAcas9: A Software Package for Designing CRISPR sgRNA and Evaluating Potential Off-Target Cleavage Sites

2014

期刊 PLoS ONE

作者 Shengsong Xie · Bin Shen · Chaobao Zhang · Xingxu Huang · Yonglian Zhang

An Androgen Receptor-MicroRNA-29a Regulatory Circuitry in Mouse Epididymis

2013

期刊 Journal of Biological Chemistry

作者 Wubin Ma · Shuanggang Hu · Guangxin Yao · Shengsong Xie · Minjie Ni · Qiang Liu · Xinxing Gao · Jun Zhang · Xingxu Huang · Yonglian Zhang

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Integrative analysis of transcriptomic and metabolomic profiles reveal the complex molecular regulatory network of meat quality in Enshi black pigs

CMAS and ST3GAL4 Play an Important Role in the Adsorption of Influenza Virus by Affecting the Synthesis of Sialic Acid Receptors

The Advancements, Challenges and Future Implications of the CRISPR/Cas9 System in Swine Research

Application of CRISPR-Cas12a Enhanced Fluorescence Assay Coupled with Nucleic Acid Amplification for the Sensitive Detection of African Swine Fever Virus

CRISPR screening of porcine sgRNA library identifies host factors associated with Japanese encephalitis virus replication

Enhancing the antibacterial activities of sow milk via site-specific knock-in of a lactoferrin gene in pigs using CRISPR/Cas9 technology

Genome editing with the CRISPR‐Cas system: an art, ethics and global regulatory perspective

Genome-Wide Patterns of Homozygosity and Relevant Characterizations on the Population Structure in Piétrain Pigs

Identification of ACTB Gene as a Potential Safe Harbor Locus in Pig Genome

Knockout of glutathione peroxidase 5 down-regulates the piRNAs in the caput epididymidis of aged mice

miR-208b modulating skeletal muscle development and energy homoeostasis through targeting distinct targets

Selective sweep analysis reveals extensive parallel selection traits between large white and Duroc pigs

Evaluation of the effects of sequence length and microsatellite instability on single-guide RNA activity and specificity

Identification of Glyceraldehyde-3-Phosphate Dehydrogenase Gene as an Alternative Safe Harbor Locus in Pig Genome

Identifying Selection Signatures for Backfat Thickness in Yorkshire Pigs Highlights New Regions Affecting Fat Metabolism

Japanese Encephalitis Virus infection induces inflammation of swine testis through RIG-I—NF-ĸB signaling pathway

Production of homeobox A10 gene transgenic pigs by somatic cell nuclear transfer

Quantification of allelic differential expression using a simple Fluorescence primer PCR-RFLP-based method

A Review of CRISPR-Based Genome Editing: Survival, Evolution and Challenges

CRISPR/Cas9‐mediated genome editing reveals the synergistic effects of β‐defensin family members on sperm maturation in rat epididymis

DICER1 regulates antibacterial function of epididymis by modulating transcription of β-defensins

Genomic Analysis To Identify Signatures of Artificial Selection and Loci Associated with Important Economic Traits in Duroc Pigs

Identifying artificial selection signals in the chicken genome

sRNAPrimerDB: comprehensive primer design and search web service for small non-coding RNAs

Alleviation of Toxicity Caused by Overactivation of P parα through P parα -Inducible miR-181a2

CRISPR-offinder: a CRISPR guide RNA design and off-target searching tool for user-defined protospacer adjacent motif

Expression of tamoxifen-inducible CRE recombinase in Lcn5-CreERT2 transgenic mouse caput epididymis

Epididymal Region-Specific miRNA Expression and DNA Methylation and Their Roles in Controlling Gene Expression in Rats

sgRNAcas9: A Software Package for Designing CRISPR sgRNA and Evaluating Potential Off-Target Cleavage Sites

An Androgen Receptor-MicroRNA-29a Regulatory Circuitry in Mouse Epididymis