array(2) { ["lab"]=> string(4) "1409" ["publication"]=> string(5) "12482" } CYP1A/regucalcin gene expression and edema formation in zebrafish embryos exposed to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin - Liang Yong | LabXing

Liang Yong

简介 中藥質量控制資訊系統，生物資訊學

大学 Macau University of Science and Technology / Faculty of Information Technology
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CYP1A/regucalcin gene expression and edema formation in zebrafish embryos exposed to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin

2008
期刊 Bulletin of environmental contamination and toxicology
作者 Yd Wu · L Jiang · Z Zhou · Mh Zheng · J. Zhang · Y Liang
In this study, zebrafish eggs were exposed to a relatively low concentration (50 pg/mL) of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) for 72 h and then transferred to vehicle/TCDD-free water for the remainder of the experiments. Mortality, heart rates, edema severity, CYP1A, and regucalcin gene expressions were investigated to study TCDD-induced toxicity in zebrafish during the early life stage. Results indicated that the 50 pg/mL TCDD caused severe and visible developmental toxicity. Further research of the long term and low concentration of TCDD exposure is required.

  • 卷 80
  • 期 6
  • 页码 482-486
  • Springer-Verlag
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