Cardiovascular (Zhang Lab)

MACMIC Reveals A Dual Role of CTCF in Epigenetic Regulation of Cell Identity Genes

2021

期刊 Genomics, Proteomics & Bioinformatics

作者 Guangyu Wang · Bo Xia · Man Zhou · Jie Lv · Dongyu Zhao · Yanqiang Li · Yiwen Bu · Xin Wang · John P. Cooke · Qi Cao · Min Gyu Lee · Lili Zhang · Kaifu Chen

Antihistamine Drug Ebastine Inhibits Cancer Growth by Targeting Polycomb Group Protein EZH2

2020

期刊 Molecular Cancer Therapeutics

作者 Qiaqia Li · Kilia Y. Liu · Qipeng Liu · Guangyu Wang · Weihua Jiang · Qingshu Meng · Yang Yi · Yongyong Yang · Rui Wang · Sen Zhu · Chao Li · Longxiang Wu · Dongyu Zhao · Lin Yan · Lili Zhang · Jung-Sun Kim · Xiongbing Zu · Anthony J. Kozielski · Wei Qian · Jenny C. Chang · Akash Patnaik · Kaifu Chen · Qi Cao

Broad genic repression domains signify enhanced silencing of oncogenes

2020

期刊 Nature Communications

作者 Dongyu Zhao · Lili Zhang · Min Zhang · Bo Xia · Jie Lv · Xinlei Gao · Guangyu Wang · Qingshu Meng · Yang Yi · Sen Zhu · Alin S. Tomoiaga · Min Gyu Lee · John P. Cooke · Qi Cao · Kaifu Chen

Machine learning uncovers cell identity regulator by histone code

2020

期刊 Nature Communications

作者 Bo Xia · Dongyu Zhao · Guangyu Wang · Min Zhang · Jie Lv · Alin S. Tomoiaga · Yanqiang Li · Xin Wang · Shu Meng · John P. Cooke · Qi Cao · Lili Zhang · Kaifu Chen

TADsplimer reveals splits and mergers of topologically associating domains for epigenetic regulation of transcription

2020

期刊 Genome Biology

作者 Guangyu Wang · Qingshu Meng · Bo Xia · Shuo Zhang · Jie Lv · Dongyu Zhao · Yanqiang Li · Xin Wang · Lili Zhang · John P. Cooke · Qi Cao · Kaifu Chen

BMI1 is directly regulated by androgen receptor to promote castration-resistance in prostate cancer

2019

期刊 Oncogene

作者 Sen Zhu · Dongyu Zhao · Chao Li · Qiaqia Li · Weihua Jiang · Qipeng Liu · Rui Wang · Ladan Fazli · Yinan Li · Lili Zhang · Yang Yi · Qingshu Meng · Wanyi Wang · Guangyu Wang · Min Zhang · Xiongbing Zu · Wei Zhao · Tuo Deng · Jindan Yu · Xuesen Dong · Kaifu Chen · Qi Cao

Polycomb group proteins EZH2 and EED directly regulate androgen receptor in advanced prostate cancer

2019

期刊 International Journal of Cancer

作者 Qipeng Liu · Guangyu Wang · Qiaqia Li · Weihua Jiang · Jung-Sun Kim · Rui Wang · Sen Zhu · Xiaoju Wang · Lin Yan · Yang Yi · Lili Zhang · Qingshu Meng · Chao Li · Dongyu Zhao · Yuanyuan Qiao · Yong Li · Demirkan B. Gursel · Arul M. Chinnaiyan · Kaifu Chen · Qi Cao

Mitochondrial DNA oxidation induces imbalanced activity of NLRP3/NLRP6 inflammasomes by activation of caspase-8 and BRCC36 in dry eye

2017

期刊 Journal of Autoimmunity

作者 Wei Chi · Xia Hua · Xin Chen · Fang Bian · Xiaoyong Yuan · Lili Zhang · Xiaoran Wang · Ding Chen · Ruzhi Deng · Zhijie Li · Yizhi Liu · Cintia S. De Paiva · Stephen C. Pflugfelder · De-Quan Li

Blueberry Component Pterostilbene Protects Corneal Epithelial Cells from Inflammation via Anti-oxidative Pathway

2016

期刊 Scientific Reports

作者 Jin Li · Ruzhi Deng · Xia Hua · Lili Zhang · Fan Lu · Terry G. Coursey · Stephen C. Pflugfelder · De-Quan Li

Pollen/TLR4 Innate Immunity Signaling Initiates IL-33/ST2/Th2 Pathways in Allergic Inflammation

2016

期刊 Scientific Reports

作者 Jin Li · Lili Zhang · Xin Chen · Ding Chen · Xia Hua · Fang Bian · Ruzhi Deng · Fan Lu · Zhijie Li · Stephen C. Pflugfelder · De-Quan Li

Broad H3K4me3 is associated with increased transcription elongation and enhancer activity at tumor-suppressor genes

2015

期刊 Nature Genetics

作者 Kaifu Chen · Zhong Chen · Dayong Wu · Lili Zhang · Xueqiu Lin · Jianzhong Su · Benjamin Rodriguez · Yuanxin Xi · Zheng Xia · Xi Chen · Xiaobing Shi · Qianben Wang · Wei Li

Effects of Azithromycin on Gene Expression Profiles of Proinflammatory and Anti-inflammatory Mediators in the Eyelid Margin and Conjunctiva of Patients With Meibomian Gland Disease

2015

期刊 JAMA Ophthalmology

作者 Lili Zhang · Zhitao Su · Zongduan Zhang · Jing Lin · De-Quan Li · Stephen C. Pflugfelder

Oxidative Stress Markers Induced by Hyperosmolarity in Primary Human Corneal Epithelial Cells

2015

期刊 PLOS ONE

作者 Ruzhi Deng · Xia Hua · Jin Li · Wei Chi · Zongduan Zhang · Fan Lu · Lili Zhang · Stephen C. Pflugfelder · De-Quan Li

A potential link between bacterial pathogens and allergic conjunctivitis by dendritic cells

2014

期刊 Experimental Eye Research

作者 Ruzhi Deng · Zhitao Su · Fan Lu · Lili Zhang · Jing Lin · Xiaobo Zhang · Cintia S. De Paiva · Stephen C. Pflugfelder · De-Quan Li

A Novel Interleukin 33/ST2 Signaling Regulates Inflammatory Response in Human Corneal Epithelium

2013

期刊 PLoS ONE

作者 Jing Lin · Lili Zhang · Guiqiu Zhao · Zhitao Su · Ruzhi Deng · Stephen C. Pflugfelder · De-Quan Li

Potential autocrine regulation of interleukin-33/ST2 signaling of dendritic cells in allergic inflammation

2013

期刊 Mucosal Immunology

作者 Z Su · J. Lin · F Lu · X. Zhang · L. Zhang · N B Gandhi · C S De Paiva · S C Pflugfelder · D.q. Li

TLR-mediated Induction of Proinflammatory Cytokine IL-32 in Corneal Epithelium

2013

期刊 Current Eye Research

作者 Lili Zhang · Chengye Che · Jing Lin · Kuixiang Liu · De-Quan Li · Guiqiu Zhao

A Native-Like Corneal Construct Using Donor Corneal Stroma for Tissue Engineering

2012

期刊 PLoS ONE

作者 Jing Lin · Kyung-Chul Yoon · Lili Zhang · Zhitao Su · Rong Lü · Ping Ma · Cintia S. De Paiva · Stephen C. Pflugfelder · De-Quan Li

Transcription Factor TCF4 Maintains the Properties of Human Corneal Epithelial Stem Cells

2012

期刊 Stem Cells

作者 Rong Lü · Yangluowa Qu · Jian Ge · Lili Zhang · Zhitao Su · Stephen C. Pflugfelder · De-Quan Li

A Novel Epithelial Proallergic Cytokine IL‐33 Serves As A Biomarker For Ocular Allergic Inflammation

2011

期刊 The FASEB Journal

作者 Lili Zhang · Guiqiu Zhao · Cintia S. De Paiva · Stephen C. Pflugfelder · De-Quan Li

Short ragweed pollen triggers allergic inflammation through Toll-like receptor 4–dependent thymic stromal lymphopoietin/OX40 ligand/OX40 signaling pathways

2011

期刊 Journal of Allergy and Clinical Immunology

作者 De-Quan Li · Lili Zhang · Stephen C. Pflugfelder · Cintia S. De Paiva · Xiaobo Zhang · Guiqiu Zhao · Xiaofen Zheng · Zhitao Su · Yangluowa Qu

TLR-mediated induction of pro-allergic cytokine IL-33 in ocular mucosal epithelium

2011

期刊 The International Journal of Biochemistry & Cell Biology

作者 Lili Zhang · Rong Lü · Guiqiu Zhao · Stephen C. Pflugfelder · De-Quan Li

An Immunoprotective Privilege of Corneal Epithelial Stem Cells Against Th17 Inflammatory Stress by Producing Glial Cell-Derived Neurotrophic Factor

2010

期刊 Stem Cells

作者 Fang Bian · Hong Qi · Ping Ma · Lili Zhang · Kyung-Chul Yoon · Stephen C. Pflugfelder · De-Quan Li

Suppressive Effects of Azithromycin on Zymosan-Induced Production of Proinflammatory Mediators by Human Corneal Epithelial Cells

2010

期刊 Investigative Opthalmology & Visual Science

作者 De-Quan Li · Nan Zhou · Lili Zhang · Ping Ma · Stephen C. Pflugfelder

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MACMIC Reveals A Dual Role of CTCF in Epigenetic Regulation of Cell Identity Genes

Antihistamine Drug Ebastine Inhibits Cancer Growth by Targeting Polycomb Group Protein EZH2

Broad genic repression domains signify enhanced silencing of oncogenes

Machine learning uncovers cell identity regulator by histone code

TADsplimer reveals splits and mergers of topologically associating domains for epigenetic regulation of transcription

BMI1 is directly regulated by androgen receptor to promote castration-resistance in prostate cancer

Polycomb group proteins EZH2 and EED directly regulate androgen receptor in advanced prostate cancer

Mitochondrial DNA oxidation induces imbalanced activity of NLRP3/NLRP6 inflammasomes by activation of caspase-8 and BRCC36 in dry eye

Blueberry Component Pterostilbene Protects Corneal Epithelial Cells from Inflammation via Anti-oxidative Pathway

Pollen/TLR4 Innate Immunity Signaling Initiates IL-33/ST2/Th2 Pathways in Allergic Inflammation

Broad H3K4me3 is associated with increased transcription elongation and enhancer activity at tumor-suppressor genes

Effects of Azithromycin on Gene Expression Profiles of Proinflammatory and Anti-inflammatory Mediators in the Eyelid Margin and Conjunctiva of Patients With Meibomian Gland Disease

Oxidative Stress Markers Induced by Hyperosmolarity in Primary Human Corneal Epithelial Cells

A potential link between bacterial pathogens and allergic conjunctivitis by dendritic cells

A Novel Interleukin 33/ST2 Signaling Regulates Inflammatory Response in Human Corneal Epithelium

Potential autocrine regulation of interleukin-33/ST2 signaling of dendritic cells in allergic inflammation

TLR-mediated Induction of Proinflammatory Cytokine IL-32 in Corneal Epithelium

A Native-Like Corneal Construct Using Donor Corneal Stroma for Tissue Engineering

Transcription Factor TCF4 Maintains the Properties of Human Corneal Epithelial Stem Cells

A Novel Epithelial Proallergic Cytokine IL‐33 Serves As A Biomarker For Ocular Allergic Inflammation

Short ragweed pollen triggers allergic inflammation through Toll-like receptor 4–dependent thymic stromal lymphopoietin/OX40 ligand/OX40 signaling pathways

TLR-mediated induction of pro-allergic cytokine IL-33 in ocular mucosal epithelium

An Immunoprotective Privilege of Corneal Epithelial Stem Cells Against Th17 Inflammatory Stress by Producing Glial Cell-Derived Neurotrophic Factor

Suppressive Effects of Azithromycin on Zymosan-Induced Production of Proinflammatory Mediators by Human Corneal Epithelial Cells