实验室简介
Our lab is interested in studying the peripheral immune and neural mechanisms of arthritis pain using a combination of approaches including immunostaining, mouse behavior, in vivo and in vitro DRG electrophysiology and calcium imaging, molecular biology and transgenic mice.
Research Summary
Treatment for joint pain in rheumatoid arthritis (RA) continues to be a challenge and represents a large unmet medical need. Although RA pain is often thought to result from inflammation, it often persists even after optimal control of inflammation with currently available therapies, indicating the involvements of other non-inflammatory mechanisms. Our lab is exploring the potential inflammation-independent mechanisms of RA pain using mouse genetics and behavioral/physiological approaches. Mor...