We are interested in understanding the regulatory mechanisms of ion channels, which is a special type of protein located in the cell membrane structure. In addition, we are seeking regulators of ion channels from natural products, such as active compounds of Chinese traditional medicine.
Multiple techniques associated with the patch clamp, membrane capacitance recording, amperometry, optical imaging of fluorescent indicator dyes and fluorescent proteins, and FRET are employed in our lab for precise deciphering the rapid signaling transduction network.
1. 离子通道功能研究
运用膜片钳等电生理技术,结合荧光显微成像和超分辨成像技术,聚焦离子通道的功能及其与疾病的关系。